Endocrine Abstracts

Introduction: Hypovitaminosis D is a biochemical change with high prevalence among the population, especially in obese patients. Its function more known relates to bones metabolism, although recently, many functions have been described.Methods: A descriptive cross-sectional study, which included women over 18 years old with BMI equal or superior of 25 kg/m2. Anthropometric measurements were obtained: weight, height, BMI, waist circumference, h...

Background: Papillary thyroid carcinomas are the most common thyroid malignancies. They are more prevalent in women and have a bimodal age distribution. Thyroglossal duct cyst carcinomas are extremely rare (occurring in only 1% of all thyroglossal duct cysts). The large majority of these carcinomas are of thyroid origin.Case presentation: A 25-year-old woman with no significant medical history was referred to the Endocrinologist with 1-month complaints o...

Introduction: Hyperglycemia (irrespective of the presence of diabetes) has been associated with worse outcomes in hospitalized patients with a variety of diseases, namely critical illness. It is been recently proposed that a relative hyperglycemia – Stress Hyperglycemia Ratio (SHR) – might be even better associated with disease outcomes. We studied how SHR correlated with various morbidity parameters in hospitalized patients due to acute pyelonephritis.<p class="...

The analogues of GLP-1(aGLP1) are a new class of anti-diabetic agents, administered subcutaneously for the treatment of Diabetes Mellitus type 2 (DM2). In the Portuguese market, there are two aGLP1 currently available: Liraglutide (once-daily administration) and Exenatide (once-weekly administration). They mimic the GLP-1, produced in the small intestine, stimulated by foods at this region, increasing the production of insulin, decreasing the satiety and slowing gastric emptyi...

Introduction: The diagnosis of infected ulcer is mainly clinical. The goals of the microbiological studies are identification of the pathogen and evaluation of susceptibility to antibiotics to minimize exposure to drugs and selection of resistant strains.Methods: Retrospective cohort study; Data collection: 1 January 2010 to 31 December 2014. Were included wound samples of aspirate, nonsurgical/surgical exudate, pus from abscesses and bone fragments from...

Introduction: Fragility fractures are the main consequence of osteoporosis. It results in increased morbidity and mortality. The incidence of fractures has been increasing steadily in Portugal. Hip fragility fractures have been estimated to occur in up to 572/100,000/year in women and up to 232/100,000/year in men.Methods: A retrospective study of hospitalized patients for femoral neck fracture in our institution in 2018 was performed to evaluate their p...

Short bowel syndrome (SBS) is a complex disease, occurring after extensive resection of the small intestine, leading to malabsorption of nutrients and fluids. Lipids storage significantly affects bone maintenance. Caloric restriction promotes bone and adipose tissue (AT) loss but marrow adipose tissue (MAT) expansion. SBS is a condition strongly associated with malnutrition; patient survival initially depends of caloric replacement through parenteral nutrition (PN). The presen...